Welcome back temperature sleuths! Today we are discussing another important storage temperature within the life sciences industry. The Ultracold or -80°C temperature is another crucial temperature for long term storage of materials that require stable, controlled, deeply frozen environments. The ultracold temperature is essential in storage of biological materials to stunt or stop degradation of samples at the cellular level over time. The -80°C temperature stops the degradation of nucleic acids, proteins, endocrine molecules, and many other biological molecules.
If you are considering the purchase of an ultracold freezer, as a first step you should develop a clear list of user requirements. This includes operating range and control accuracy of the unit. You can also differentiate between ultracold freezer compressor technology. You should investigate ultracold freezers that do not use old compressor technology as wear and tear of compressors affects the cooling of the unit over a shorter and longer period. Older oil compressor technology creates large valleys and peaks within defrost cycles which in turn affects sample stability and degradation. Ultracold freezers that use free-piston engines which use a reciprocating piston and displacer, along with a continuous gravity driven thermosiphon cool the ultracold freezer cabinet interior while allowing for less valleys and peaks within defrost cycles and a more stable freezer environment to protect biological samples.